Clinical Scientist

COMPANY OVERVIEWAIRNA is a biotechnology company with a mission to be the leading RNA editing company delivering precision therapies to patients with rare and common diseases. AIRNA is harnessing advances in genetics to develop transformative RNA-editing medicines that improve human health. Our proprietary platform is based on groundbreaking research by pioneers of the field and company co-founders Thorsten Stafforst (University of Tübingen) and Jin Billy Li (Stanford University) and enables optimal potency, safety, and delivery. AIRNA is advancing a robust pipeline of therapeutic candidates that are designed to provide functional cures for severe or chronic diseases by repairing harmful genetic variants or introducing beneficial variants promote optimal health. AIRNA has raised $245 million in financing from a world-class syndicate of investors including Arch Venture Partners, Forbion, Venrock Healthcare Capital Partners, RTW Investments, Nextech Invest, and ND Capital. We value teamwork, resilience, excellence, human, and health, and have a diverse team at both our headquarters in Cambridge, MA and our research operations in Tübingen, Germany.JOB OVERVIEWThe Clinical Scientist supports the design, execution, and analysis of clinical trials that are part of AIRNA’s RNA editing platform. Working closely with Clinical Development, Clinical Operations, and external clinical trial site staff, the clinical scientist will ensure scientific integrity and operational excellence in AIRNA’s clinical trials.RESPONSIBILITIESClinical Trial Design & Protocol DevelopmentAssist in or lead the design of clinical study protocols and amendmentsWrite or contribute to study-related documents (e.g., IB, informed consent forms, CRFs, recruitment materials)Study Execution SupportProvide scientific and clinical input during trial conductMonitor data for consistency, completeness, and potential safety/efficacy signalsCollaborate with CROs, sites, and internal teams to resolve study-related issuesBuild relationships with sites including PIs and clinical trial site staff, supporting their start up activities and patient recruitment activitiesData Analysis & InterpretationReview clinical trial data in collaboration with data management and biostatisticsInterpret data in the context of the disease, target, and competitive landscapeContribute to clinical study reports and documentation for regulatory submissionsCross-functional CollaborationWork closely with Clinical Operations, Medical Monitors, Pharmacovigilance, and Regulatory AffairsParticipate in clinical development plan creation and updatesPresent study results and strategy to internal stakeholders and internal governance bodiesRegulatory & Safety InputSupport preparation of INDs, NDAs, CTAs and other regulatory documentsProvide input into safety review processes and risk-benefit assessmentsQUALIFICATIONS Education:Advanced degree in life sciences or health discipline (PhD, PharmD, MD, or MS with relevant experience)Experience:2–6+ years of industry experience in clinical development and/or clinical operationsSkills:Strong knowledge of ICH GCP and clinical trial methodologyAbility to critically evaluate scientific data and literatureStrong communication skills (verbal and written)Ability to manage multiple priorities and collaborate across functionsPreferred Attributes:Experience in rare disease, including pulmonary/hepatic diseasesFamiliarity with working with and supporting clinical trial sites for study start-up and recruitmentWorking knowledge of clinical trial site monitoringAbility to travel to clinical trial sites and build relationships with PIs and clinical trial site staff LOCATIONThis is a remote position that will require travel to sites. A candidate based in Europe/UK is preferred.

Created: 2025-08-01